Please select any SGLT2 inhibitors you took during or after May 2013:
Were you diagnosed with Fournier’s Gangrene by a medical professional?
Were you subject to any amputations due to side effects linked to the consumption of these drugs?
Did Symptoms begin during use or within 90 days of last ingestion?
Please describe any additional side effects you have experienced
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May 2015 Many reports of ketoacidosis and diabetic ketoacidosis (DKA) requiring hospitalization
September 2015 Label update warning about increased risk of bone fracture
December 2015 Label change for SGLT2 inhibitors about increased risk of ketoacidosis and serious urinary tract infections
May 2016 First amputation warning based on interim analysis of CANVAS and CANVAS-R studies
June 2016 Communication to doctors with stronger warnings about kidney injury risks
May 2017 Second amputation warning, requiring a label update with a boxed warning
August 2018 Invokana and other SGLT2 inhibitors may lead to a flesh-eating genital infection (Fournier’s gangrene or necrotizing fasciitis)